
Your Skin Regenerated!
Polynucleotides with Plinest®
Plinest® Polynucleotides
Cellular regeneration for lasting renewal
Regenerate tired, damaged skin at a cellular level with this innovative injectable treatment. Polynucleotides work deep within the skin to repair, hydrate and restore elasticity, making it perfect for delicate areas like under-eyes and neck. This cutting-edge treatment stimulates your skin’s own repair mechanisms for natural, long-lasting rejuvenation. The treatment represents the next generation in skin bioremodelling, working at a fundamental cellular level.


How Does It Work?
Polynucleotides are the latest revolutionary tools in regenerative medicine that work on a cellular level to repair tissue and boost skin quality.
In the form of polymerised polynucleotide-based injectable gels, polynucleotides work by stimulating fibroblasts which encourages cell turnover, improves elasticity, boosts collagen production and hydrates skin thanks to powerful wound-healing polymers.
Polynucleotides also calm inflammation and rebalance melanocyte activity to create an even and refreshed skin tone.
As the Home of Polynucleotides, DermaFocus has a selection of polynucleotides that can treat:
Fine lines
Acne scarring
Dark under-eye circles
Skin laxity
Poor tone and texture
They can also rejuvenate the scalp (PLINEST HAIR), neck, décolletage, inner arms and thighs, knees and intimate area.
We exclusively distribute leading polynucleotide brands PLINEST and NEWEST – our hero product that is combined with hyaluronic acid – from Mastelli.
Each product within the brands has its own unique formula, allowing practitioners to tackle concerns in every skin type.
More questions? Check out our FAQs
The Consultation
All treatment journeys will begin with a one-hour-long consultation with Sarah to assess suitability and to explain the treatment process, what to expect, and aftercare. This is also an opportunity for Sarah to complete a detailed medical and lifestyle history and establish if any contraindications to treatment need to be considered.
Following on from your consultation next steps will be discussed and your bespoke skin journey planned.


Who are Polynucleotides for?
- Men, Women, and Non-binary individuals over the age of 18
- Not pregnant or breastfeeding
- Those with skin concerns such as as:
- Lines & wrinkles
- Poor skin texture
- Dark under-eye circles
- Scarring
- Stretch marks
- Glycation
- Smokers lines
- Lax, loose skin
How Much Is It?













